Restoring the gut ecology behind metabolic health.
Our mission
Amara combines with modern microbial science to develop fermented medical foods for gut and metabolic health. Our approach uses plant substrates to create complex biochemical matrices to support the gut ecosystem.
Heritage fermentation: ecological fermentation driven by naturally occurring bacteria and yeast, with no industrial strains.
Multi-kingdom: controlled fermentation of bacteria and yeast guilds.
Chronic inflammation is a gut-ecology problem.
The gut is home to trillions of microbes that help shape the body’s inflammatory response. When this ecosystem is disrupted, microbial metabolism, barrier integrity, and immune signaling can become dysregulated. Amara is developing fermented medical foods designed to nourish the gut microbiome.
Understanding the matrix hypothesis.
Our gut doesn’t read nutrition facts, it recognizes biochemical matrices.
The foods and drinks we are surrounded by today are fundamentally different from what we consumed before the Industrial Revolution. In the past, foods and drinks were complex matrices in which plant compounds and metabolites interacted. Today’s ultra-processed foods destroy that matrix to be shelf-stable and robust in supply chains. At Amara, we view the fermentation matrix as the therapeutic vehicle because it is optimally bioavailable to the gut.
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Bread
Long-fermented sourdough 
Industrially produced bread -
Fruit
Whole fruit 
Fruit juice -
Coffee
Coffee 
Energy drink -
Cheese
Homemade cheese 
Industrially produced cheese -
Heritage Fermentation
Multi-kingdom fermented plant matrix (Amara Restore) 
Industrially produced yogurt
Our gut needs more fiber than we give it.
Fiber is the fuel that feeds the gut microbiome. Ultra-processed foods have left us undernourished in the fiber our gut needs, which contributes to gut imbalance. Fiber must also have the correct glycan shape to reach the colon, where gut bacteria live.
Fiber is the fuel that provides thermodynamic power for our gut bacteria. Amara’s fermentation matrix delivers more fiber so our gut bacteria work better.
Amara Restore
It is not
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A probiotic delivers live strains while Restore delivers the whole fermentation matrix.
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Kombucha lacks the fiber and resistant starch that Restore provides.
A meal replacement.
A single-ingredient supplement.
An isolated metabolite.
It is
A standardized, multi-kingdom fermented plant matrix created through interacting microbial communities. Rather than relying on a single strain, ingredient, or metabolite, Restore uses microbial guilds and cross-feeding to create a complex biochemical matrix designed to support gut ecology and metabolic health.
From heritage fermentations to standardized science.
Heritage fermentation is an approach to transforming food through the natural activity of diverse microbial communities, including bacteria and yeasts.
Select & prepare
Ferment & monitor
Stop & standardize
For clinicians & research partners
Help us build the evidence.
We welcome collaborations with clinicians, academic researchers, and healthcare organizations interested in product characterization, pilot studies, and clinical research.
Explore Research CollaborationFor individuals & consumers
Stay connected with Amara Restore.
Interested in learning more about our fermented plant matrix, research progress, and future product developments? We’d love to hear from you.
Register Your Interest